Live Cell Imaging System inside the Incubator


Time-lapse images of cells and real time analysis from inside your incubator

Specifically designed for easy parallel monitoring of 6 well plate cultures

For research use only (RUO). Not for use in diagnostic procedures.

CYTONOTE 6W Live cell imaging system

Label free & high contrast

No Zoom

Always in focus

No Settings

Settings free


Huge field of view

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Cell confluence determination

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Cell based assay, proliferation, migration, tracking, wound healing...

The simplest live cell imaging system designed for the monitoring up to 6 cell cultures in parallel

The CYTONOTE 6W uses our patented lens-less imaging technology in a tiny device design to fit within any incubator. The CYTONOTE product range simplifies live cell imaging technique and transforms the complex and expensive microscope into a cost-effective solution.

The CYTONOTE 6W is the simplest live cell-imaging system designed for recording cell movies and analyzing a variety of cell culture from inside the incubator. The innovative and patented “lens-less imaging” technology pushes the boundaries of microscopy with its super wide field of view and its capability to capture and analyze precisely several thousands of cells without any focus and brightness settings.


  • In direct from your incubator
  • Time-Lapses & Movies
  • High contrast
  • lways in focus
  • Settings free
  • Huge field of view
  • Robust
  • Many cell culture application


  • Real-Time Imaging of your cell culture
  • Up to 6 cell cultures in parallel
  • Time-Lapses and movies of your cells
  • Confluence analysis
  • Growth curves
  • Migration test
  • Proliferation test
  • Cell morphology
  • Cell population
  • Cell attachment / detachment
  • Cell tracking

How to use our live cell imaging system ?

Our Live Cell Imaging System, the CYTONOTE 6W has been designed to be compatible with all Petri dishes, T-Flask and slides. Select your container and place it on the CYTONOTE 6W. The default acquisition time between two measurements is 20 minutes. However, this time can be changed at your convenience and thus you can adapt the time periods for the realization of time-lapses of your cells.

As explained above, no adjustment of parameters such as focus or brightness is necessary. Our algorithm will reconstruct the cells wherever they are located in the container. These features make the CYTONOTE 6W robust to temperature variations, cell drop inside the Matrigel, or any other parameters that may affect the traditional focus adjustment.

What are the results of our live cell imaging system ?

Our Live Cell Imaging System,  the CYTONOTE 6W works on an ultra-wide field of view where all data recovered from picture represent your cell culture. The image analysis and results from the CYTONOTE 6W are performed by the HORUS dedicated Software. HORUS is application oriented: it provides quantitative confluence determination, cell size or cell tracking. Full field image (30mm2) of the samples are stored and can be accessed and zoomed at any time.

Iprasense Horus Software Cell Culture Monitoring and your Cell Viability

HORUS Software Included

Our best software for our live cell imaging system !

HORUS Software is included with the acquisition of our products and is regularly updated by our development team.


“What I like most about the CYTONOTE is the tracking of thousands of cells. With the microscope, you can only follow a few hundred cells… If I could not track so many cells, I would never have been able to see this new cell rhythm. This allows the discovery of new phenomena that cannot be seen with other microscopes, and this without labelling or preparation and in direct from the incubator.The 6-well system is excellent for parallel culture monitoring, especially when testing with drugs! It’s very convenient!It’s a tool that is now part of our protocols! It’s essential to have several instruments to obtain all types of information. The CYTONOTE allows to bring a lot of additional information that is not possible to get with other microscopes.”
CEA - 2021

Technical specifications

Cells Eucaryotic cells : Adherent monolayer, Suspension cell at bottom of culture ware or in micro-slides, 3D spheroids
Media Liquid or Semi-solid (collagen)
Culture Vessels Standard plastic petri dish, culture flask, multiwell plate, max height 55mm
Resolution 1 micron
Field of view 30 mm² (6,5 mm x 6,5 mm)
Working distance 0 to 5 mm
Image rate 1,5 image/min
Light source LED
Sensor CMOS 10 Mpix
Image .JPEG / .PNG / .BITMAP / .TIFF
Enclosure Stainless Steel
Dimensions 17 x 13 x 10,5 cm
Weight 2 kg
Power Supply USB
Pharmaceutical industries 21 CFR part 11 & IQ/OQ

Accessories & consumables

HORUS Software
21 CFR part 11
Scratch Assay analysis module for HORUS Software
Cell Tracking analysis module for HORUS Software
Cell Tube Formation analysis module for HORUS Software
Cytonote cable – 2 meters
Laptop computer


A Live Cell Imaging System is a cutting-edge technology that allows researchers to observe and analyze living cells in real-time within their natural environment, such as inside an incubator.

The CYTONOTE system offers high contrast, always-in-focus images, settings-free operation, a huge field of view, and robust performance.

With its patented lens-less imaging technology, the CYTONOTE eliminates the need for manual adjustments like focus and brightness settings. It provides hassle-free monitoring of up to 6 cell cultures in parallel.

The CYTONOTE system enables real-time imaging of cell cultures, time-lapses, confluence analysis, growth curves, migration and proliferation tests, cell morphology studies, cell tracking, and more.

Simply place your cell culture container, such as a Petri dish or T-flask, onto the CYTONOTE 6W. The system operates with a default acquisition time of 20 minutes between measurements, which can be adjusted as needed.

The CYTONOTE provides ultra-wide field-of-view imaging, with data analyzed using the dedicated HORUS software. Results include quantitative confluence determination, cell size analysis, cell tracking, and more.

By this product technology, there is a wide field of view, no manual adjustment step and the results are obtained in seconds.

The CYTONOTE supports various cell types and media, offers a resolution of 1 micron, a field of view of 30 mm², and operates with a CMOS 10 Mpix sensor. It’s compact, lightweight, and compatible with standard culture vessels.

Yes, accessories include cables, software modules for analysis (such as Scratch Assay and Cell Tracking), and compliance options for pharmaceutical industries (like 21 CFR part 11 and IQ/OQ).

Yes, all our products are 21 CFR.