Live Cell Imaging inside the Incubator
CYTONOTE 1W
Time-lapse images of cells and real time analysis from inside your incubator
A small footprint device that stays always in focus with Petri dishes, T-flasks, slides or microfluidic chips
For research use only (RUO). Not for use in diagnostic procedures.
CYTONOTE implements our patented Lensless Technology in a tiny device design to fit within any incubator.
The small foot print (132 cm² only!) allows you to follow any of your cell culture without any incubator adaptation or working space limitation.
Label free & high contrast
Always in focus
Settings free
Huge field of view
Cell proliferation
Cell proliferation through cell count and quantitative confluence determination
Angiogenesis
The very wide area allows to observe the full angiogenesis process with high level of details
Cell migration
Chemotaxis, wound healing on high statistical number of cells and very wide area
Time-lapse images of cells and real time analysis from inside your incubator
The CYTONOTE 1W uses our patented lens-less imaging technology in a tiny device to fit with any incubator. The CYTONOTE 1W is the simplest live cell-imaging system designed for recording cell movies and analyzing a variety of cell culture from the incubator. The innovative and patented “Lens-less imaging” technology pushes the boundaries of microscopy with its super wide field of view and its capability to capture and analyze precisely several thousands of cells without any focus and brightness settings. This technology simplifies the Live Cell Imaging technique and transforms the complex and expensive microscope method into a cost-effective solution.
FEATURES CYTONOTE 1W
- Tiny device
- In direct from your incubator
- Time-Lapse & Movie
- Many cell cultures application
- Robust
- High Contrast
- Always in focus
- Wide field of view
CYTONOTE 1W APPLICATIONS
- Real-Time Imaging of your cell culture
- Time-Lapses and Movies of your cells
- Confluence analysis
- Growth curves
- Migration test
- Proliferation test
- Cell morphology
- Cell population
- Cell attachment / detachment
- Cell tracking
How to use our cell imager analyser?
The CYTONOTE 1W is designed to be compatible with every standard lab dishes, T-flask or slides. Select your container and place it on the CYTONOTE 1W. The acquisition time between two measurements is 20 minutes by default, but you can change this time if you wish. By performing acquisitions over a give period of time you will be able to obtain time lapses and movies of your cells.
As explained, no need to adjust focus, brightness or any other parameters, our algorithm will reconstruct cells wherever cells are located… from few micrometers to some millimeters! This characteristic makes the CYTONOTE 1W an extremely robust device not fearing temperature variation, cells descent inside Matrigel, or any other parameter which can affect traditional focus adjustment.
What are the results ?
The CYTONOTE 1W works on an ultra-wide field of view, where all data recovered from picture represent your cell culture.
The image analysis and the result from the CYTONOTE 1W are performed from the HORUS dedicated Software. HORUS is application oriented: it provides quantitative confluence determination, cell size, cell tracking… Full field image (30mm2) of the sample is stored and can be accessed and zoomed at any time.
The simultaneously option
The HORUS Software has been designed to connect up to 6 CYTONOTE 1W simultaneously allowing the control of up to 6 independent parallel cell cultures.
HORUS Software Included
Our best software for cell counting and cell analysis !
HORUS Software is included with the acquisition of our products and is regularly updated by our development team.
Testimony
Technical specifications
| Cells | Eucaryotic cells : Adherent monolayer, Suspension cell at bottom of culture ware or in micro-slides, 3D spheroids |
| Media | Liquid or Semi-solid (collagen) |
| Culture Vessels | Standard plastic petri dish, culture flask, multiwell plate, max height 55mm |
| Resolution | 1 micron |
| Field of view | 30 mm² (6,5 mm x 6,5 mm) |
| Working distance | 0 to 5 mm |
| Image rate | 1,5 image/min |
| Light source | LED |
| Sensor | CMOS 10 Mpix |
| Image | .JPEG / .PNG / .BITMAP / .TIFF |
| Enclosure | Stainless Steel |
| Dimensions | 12 x 11 x 10 cm |
| Weight | 1 kg |
| Power Supply | USB |
| Pharmaceutical industries | 21 CFR part 11 & IQ/OQ |
Accessories and consumables
HORUS Software |
|---|
21 CFR part 11 |
Scratch Assay analysis module for HORUS Software |
Cell Tracking analysis module for HORUS Software |
Cell Tube Formation analysis module for HORUS Software |
Cytonote cable – 2 meters |
Laptop computer |
IQ/OQ |
F.A.Q.
A Live Cell Imaging System is a cutting-edge technology that allows researchers to observe and analyze living cells in real-time within their natural environment, such as inside an incubator.
The CYTONOTE system offers high contrast, always-in-focus images, settings-free operation, a huge field of view, and robust performance.
With its patented lens-less imaging technology, the CYTONOTE eliminates the need for manual adjustments like focus and brightness settings. It provides hassle-free monitoring of up to 6 cell cultures in parallel.
The CYTONOTE system enables real-time imaging of cell cultures, time-lapses, confluence analysis, growth curves, migration and proliferation tests, cell morphology studies, cell tracking, and more.
Simply place your cell culture container, such as a Petri dish or T-flask, onto the CYTONOTE 1W. The system operates with a default acquisition time of 20 minutes between measurements, which can be adjusted as needed.
The CYTONOTE provides ultra-wide field-of-view imaging, with data analyzed using the dedicated HORUS software. Results include quantitative confluence determination, cell size analysis, cell tracking, and more.
By this product technology, there is a wide field of view, no manual adjustment step and the results are obtained in seconds.
The CYTONOTE supports various cell types and media, offers a resolution of 1 micron, a field of view of 30 mm², and operates with a CMOS 10 Mpix sensor. It’s compact, lightweight, and compatible with standard culture vessels.
Yes, accessories include cables, software modules for analysis (such as Scratch Assay and Cell Tracking), and compliance options for pharmaceutical industries (like 21 CFR part 11 and IQ/OQ).
Yes, all our products are 21 CFR.